1 Micro electromechanical Film Bulk Acoustic Sensor for Plasma and Entire Blood Coagulation Monitoring
Kayla Matheny edited this page 2 days ago


Monitoring blood coagulation is a crucial difficulty within the surgeries and the remedy of cardiovascular diseases. In this work, we reported a novel technique for the blood coagulation monitoring based on a micro-electromechanical film bulk acoustic resonator. The resonator was excited by a lateral electric area and operated below the shear mode with a frequency of 1.9GHz. In keeping with the obvious step-ladder curves of the frequency response to the change of blood viscoelasticity, the coagulation time (prothrombin time) and the coagulation kinetics had been measured with the sample consumption of only 1μl. The procoagulant exercise of thromboplastin and the anticoagulant impact of heparin on the blood coagulation process have been illustrated exemplarily. 0.99969 and a consistency with the coefficient of variation less than 5% compared with the commercial coagulometer. The proposed movie bulk acoustic sensor, which has the advantages of small measurement, mild weight, low value, easy operation and little sample consumption, is a promising system for miniaturized, on-line and automatic analytical system for routine diagnostics of hemostatic status and personal health monitoring.


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